![]() Injecting.( 7, 8) Duration of injecting is the strongest single predictor of risk of HCV infection among injection drug Infection.( 5) Studies of injection drug users have demonstrated that the prevalence of HCV infection in them is extremely high, with up to 90% having beenĮxposed.( 6) In addition, the incidence of new infections is also high, with seroconversion rates of 10-20 percent per year of Use.( 4) In addition, rates of HCV among young injecting drug-users are four times higher than HIV In comparison to other viral infections, HCV is more rapidly acquired after initiation of intravenous drug Injection drug use has been the principal mode of transmission of HCV since the 1970's. since 1999, and have lowered the current risk of acquiring HCV via transfused blood products to 1 in 2 These techniques are estimated to have prevented 56 transfusion-associated HCV infections per year in the U.S. ![]() In the last several years, blood banks have instituted techniques that utilize nucleic acid amplification of the hepatitis C virus, which will detect the presence of virus even in newly-infected patients who are still hepatitis C antibody-negative. Status.( 1, 2) Today, HCV is rarely transmitted by blood transfusion or transplantation of organs due to thorough screening of the blood supply for the presence of the virus and inactivation procedures that destroy bloodborne viruses. The two most common exposures associated with transmission of HCV are blood transfusion and injection drug use.īlood Transfusion/Receipt of Blood ProductsĮarly case-control studies of patients with newly acquired, symptomatic non-A, non-B hepatitis found a significant association between disease acquisition and a history six months prior to illness of blood transfusions, injection drug use, health care employment with frequent exposure to blood, personal contact with others who had hepatitis, multiple sexual partners or low socioeconomic It is clear that HCV is most frequently transmitted through large or repeated direct percutaneous exposures to infected blood. Some modes of transmission of hepatitis C virus are well documented and widely accepted others are less well defined and require further study. ![]()
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